- A 1.5% Solution of Glycine (Amino acetic acid) contains 0.15 mg/ml of glycine.
Actions and Indications.
Glycine irrigation is non haemolytic and non-conductive and has a refractory index close to that of water, mmaking it useful as a urologic irrigating solution, particularly during transurethral surgical procedures where the irrigating fluid may be absorbed systematically through cut venous sinsus. Beacause of its nonconductive property, glycine irrigation may be useful as a urologic irrigany during electro surgical procedures.
In the absence of accompanying calorie substrate, systemically absorbed glycine is metabolized mainly by deamination to ammonia and transamination to other amino acids.
Dosage and Administration.
Glycine Irrigation Solution is administered during urologic irrigation, via an administration set connected to an indwelling utrthral catheter designed for continuous or intermittent two-way flow.
Irrigation solution must not be administered by parenteral injection.
Dosage of an Irrigation Solution depends on the capacity or surface area of the structure to be irrigated and the nature of the procedure.
Glycine irrigation should be used with caution in patients with known or suspected hepatic impairment since absorption and resultant metabolism of glycine may result in increased blood concentrations of ammonia in such patiens. Glycine irrigation is contraindicated in patients with anuria.
1.5% Glycine Solution in 5L bag